Realign
your expectations of oral enzymes.
your expectations of oral enzymes.
how diseases of malabsorption and nutrient metabolism can be treated.
what's possible.
breakthrough orally-delivered enzyme therapeutics engineered for rare, life-threatening diseases.
Malabsorption Syndromes and Nutrient Metabolism Disorders are a group of disorders caused by enzyme deficiencies or genetic mutations that result in conditions that prevent the body from properly metabolizing or absorbing certain fats, carbohydrates, simple sugars, proteins, vitamins or other key nutrients.
Steatorrhea, constipation, nausea, abdominal pain, bloating, gas, diarrhea
Weight loss, wasting and fatigue are common and pronounced; independent predictor of survival
Play a central role in severity of symptoms and disease progression
Worsens clinical outcomes; adds to the overall costs of care and dramatic impact to QoL
Directly impacts survival in rare disease, cancer and pancreatitis
Increased inflammation, vitamin deficiencies, reduced bone mineral metabolism and ultimately organ failure
Through this specific and selective approach, our team of world-class researchers and collaborators is unlocking breakthrough orally-delivered enzyme therapeutics that have the potential to change how Malabsorption Syndromes and Nutrient Metabolism Disorders are treated.
At Anagram, we are developing a deep pipeline of products that use the power of orally-delivered enzymes as therapeutics to solve complex problems.
New class of enzyme replacement therapy providing unparalleled performance with broad-spectrum composition (lipase for fat, protease for protein, amylase for carbohydrate) to make a life-changing impact for people who require oral ERT.
Engineered to break down specific carbohydrates due to enzyme deficiencies to avoid the severe complications associated with carbohydrate malabsorption.
Engineered to break down specific carbohydrates abnormalities due to pancreatic dysfunction to avoid the complications associated with carbohydrate malabsorption.
Engineered to break down specific carbohydrates to avoid buildup in the body of toxic complications associated with carbohydrate malabsorption.
Anagram's team of passionate scientists and biotech leaders are united in our commitment to individuals and families affected by serious rare diseases. We are focused to our core and driven to take on big challenges in our pursuit of big breakthroughs and better therapies.
Together, we are working to turn potential into products, and meaningfully improve the lives of people living with Malabsorption Syndromes and Nutrient Metabolism Disorders.
Take a look at our Management Team and Board of Directors.
Anagram is looking for team members who are talented, engaged and committed to growing the organization through the work that they do. Join our team of leading scientists, expert drug developers, and biotech industry veterans. We offer competitive salary and benefits, as well as an environment where excellence and creativity make meaningful scientific and medical advances possible.
Anagram Therapeutics, Inc. | 10 Speen Street | Framingham, MA 01701
617-466-3111
